Jeff Barrett is the eponymous leader of the Barrett Group. Originally from Boston, Massachusetts, he moved to Oxford for a PhD in Statistical Genetics with Lon Cardon. He established the Medical Genomics group at the Wellcome Trust Sanger Institute in 2008. Jeff has also been Director of the Open Targets since 2015.
Dan Rice is a senior software developer creating applications in javascript and python. With degrees in computing and maths, he has worked in the private and military industries. Being half American/half British, he is friendly and upbeat but also apologetic about this.
Liu He is a postdoc currently working on deciphering the genetic component of Autism Spectrum Disorder. Coming from Shanghai, China, he used to work on the evolutionary aspects of gene expression and regulation in the human brain. Other than pursuing science, his more recent life goal is to shake the 10 pounds bestowed by the great English food. With the exceptionally clean air for all kinds of outdoor activity here, he believes it could be accomplished in 3 years time.
Mari Niemi is a PhD student who’s currently looking into the effects of common variation on the clinical presentation of DDD patients. Mari originally emerged from the forests of Finland to study biomedical science and human genetics, but still likes to retreat back into the woods whenever possible.
Hilary Martin is a postdoc working on the Deciphering Developmental Disorders (DDD) study and the East London Genes and Health (ELGH) project. She is currently focused on estimating the contribution of recessive disorders to the DDD. In ELGH, she studies the genomes of highly consanguineous individuals to identify complete gene knockouts that could be informative about gene function or potential new drug targets. An Australian, Hilary came to Sanger via Oxford, where she worked on clinical genome sequencing, patterns of recombination in humans, and population genetics of the platypus.
Alex Sazonovs is a PhD student in the group. Originally from Latvia, he came to the UK to study computer science at the University of St Andrews. Alex is now working on working on the analysis of our IBD sequencing data.
Juliet Handsaker is a joint PhD student with Matt Hurles…

Barrett group alumni


Kate Morley was a postdoctoral statistical genetics analyst in the group from 2009 to 2012. She is now a Lecturer in the Addictions Department of the Institute of Psychiatry at KCL. Kate was the group’s first full time employee, and was sadly also the first to move on.
Luke Jostins was the Barrett group’s first PhD student, finishing in 2012. He has since moved on to a Sir Henry Wellcome postdoctoral fellowship in Oxford, but maintains close links with our group.
Iris Kolder was a postdoctoral research fellow who spent a year with the group working on next generation sequence analysis before moving back to the Netherlands.
James Morris was our key Bioinformatician for four-and-a-half years, and was the principal software developer for many of the programs we’ve released. In 2014 James moved to the Rosenfeld lab at the CRUK Cambridge Institute, down the road from Sanger.
Isabelle Cleynen visited the lab in 2013 from KU Leuven as a postdoctoral research fellow. She is now a Professor back in Belgium, continuing to collaborate on IBD genetics projects.
Douglas Porter was a visiting summer student in 2014 from the University of Wisconsin. He’s analyzing data from the mitochondrial genome in the DDD project.
Yang Luo was a postdoctoral fellow in the lab from 2011 to 2015. She led our TB and IBD sequencing projects, and has now joined Soumya Raychaudhuri’s lab at Harvard.
Sarah Spain was a postdoctoral statistical geneticist in the lab who worked on analyses in Open Targets, where she has now moved as a project manager.
Tarjinder Singh was a grad student in the group. He worked on exome sequence analysis in neurodevelopmental disorders, and is now a postdoc with Mark Daly in Boston.
Wendy Jones was a clinical PhD student in the lab. She worked on the DDD project, and is now a consultant clinical geneticist at Great Ormond Street Hopsital in London.
Maša Mirkov was a postdoc working on IBD fine-mapping who has moved on to the Posthuma lab in Amsterdam.
Katie de Lange was a PhD student working on IBD genome sequencing, and is now a research fellow at Vertex Pharmaceuticals in Boston.
John Lees was a joint PhD student working on host-pathogen genomic interactions, who is now doing a postdoc in New York City.
Jeremy McRae was a postdoc working on DDD, who has moved on to Illumina in sunny California.