17. October 2017 · Comments Off on We’re hiring! · Categories: Uncategorized

We’re currently looking to recruit new postdoctoral fellows for a variety of projects:

  • Microbiome analysis: We have begun to generate shotgun metagenomes in thousands of IBD patients to study disease inception, progression and response to treatment. We are looking for an experience microbiome analyst interested in leading these projects and building on our substantial clinical and data generation resources.
  • High throughput cellular screens: In order to better understand GWAS and rare variant associations we are setting up a number of cellular models for key bits of IBD and developmental biology, including iPSC derived neurons and macrophages, immortal cell lines and primary cells. We’re looking for wet or wet/dry postdocs interested in developing high throughput CRISPR screens (both pooled and well-based) in these models to better understand the function of associated genetic variants.
  • Statistical genetics methodology: As we generate ever-larger whole genome sequence datasets we’re looking to build tools to enable new analyses. For example, we have an ongoing project using deep convolutional networks to predict local indel mutation rates to better calibrate discovery of causal mutations in severe developmental disorders.
  • Statistical genetics data analysis: Similarly, we’re looking for postdocs interested in analysis of datasets of tens of thousands of sequenced genomes to ask and answer biological questions about disease.

Official postings will appear soon on the Sanger jobs website, but please get in touch directly if you’re interested in the meantime!

18. September 2016 · Comments Off on About us · Categories: Uncategorized

playground-journal-clubThe Barrett group works on medical genomics research at the Wellcome Trust Sanger Institute. We are interested in how genetic variation affects risk for diseases, and in finding ways to apply that knowledge to improve health care. We analyze genome-wide association studies and next-generation sequence data collected on thousands of individuals, and develop statistical and computational methods for these analyses.

You can keep up to date with news and posts about our research by subscribing to our RSS feed.

29. April 2013 · Comments Off on Team retreat 2013 · Categories: Uncategorized · Tags: , , , , , , ,

Lichfield Cathedral
On the weekend of 22nd of March, we went on our annual team retreat to Waterhouses, a village in the south of the Staffordshire Peak District. We set off from Oxford following a symposium at the Wellcome Trust Center of Human Genetics. Along the way we stopped in Lichfield to visit the famous Cathedral and the house of Erasmus Darwin (grandfather of Charles Darwin, www.erasmusdarwin.org). Surprisingly, Erasmus Darwin’s work hinted at the possibility of evolution, and although they had never met, Charles’ inspiration could have potentially come from his grandfather. We also had a nice meal in the Damn Fine Café, which had a selection of food and drink perfect for a cold winter’s afternoon.

We were really fortunate not to have lingered too long in Lichfield, as a large snowstorm rapidly descended upon the region. More »